5NSG

Fc DEDE homodimer variant

Summary for 5NSG

Entry DOI	10.2210/pdb5nsg/pdb
Descriptor	Putative uncharacterized protein DKFZp686C11235, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ZINC ION, ... (5 entities in total)
Functional Keywords	igg, fc homodimer, l351d/l368e + l351d/l368e, immune system
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	27691.96
Authors	De Nardis, C.,Hendriks, L.J.A.,Poirier, E.,Arvinte, T.,Gros, P.,Bakker, A.B.H.,de Kruif, J. (deposition date: 2017-04-26, release date: 2017-07-05, Last modification date: 2024-01-17)
Primary citation	De Nardis, C.,Hendriks, L.J.A.,Poirier, E.,Arvinte, T.,Gros, P.,Bakker, A.B.H.,de Kruif, J. A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G1. J. Biol. Chem., 292:14706-14717, 2017 Cited by PubMed: 28655766 DOI: 10.1074/jbc.M117.793497 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.22 Å)

Structure validation