5NQA
Crystal structure of GalNAc-T4 in complex with the monoglycopeptide 3
Summary for 5NQA
Entry DOI | 10.2210/pdb5nqa/pdb |
Descriptor | Polypeptide N-acetylgalactosaminyltransferase 4, Monoglycopeptide 3, 1,2-ETHANEDIOL, ... (6 entities in total) |
Functional Keywords | galnac-t4, galnac-t2, chimeras, glycosylation preferences, std-nmr, flexible linker, transferase |
Biological source | Homo sapiens (Human) More |
Cellular location | Golgi apparatus membrane ; Single-pass type II membrane protein : Q8N4A0 |
Total number of polymer chains | 3 |
Total formula weight | 140480.98 |
Authors | de las Rivas, M.,Lira-Navarrete, E.,Daniel, E.J.P.,Companon, I.,Coelho, H.,Diniz, A.,Jimenez-Barbero, J.,Peregrina, J.M.,Clausen, H.,Corzana, F.,Marcelo, F.,Jimenez-Oses, G.,Gerken, T.A.,Hurtado-Guerrero, R. (deposition date: 2017-04-19, release date: 2017-12-20, Last modification date: 2024-01-17) |
Primary citation | Rivas, M.L.,Lira-Navarrete, E.,Daniel, E.J.P.,Companon, I.,Coelho, H.,Diniz, A.,Jimenez-Barbero, J.,Peregrina, J.M.,Clausen, H.,Corzana, F.,Marcelo, F.,Jimenez-Oses, G.,Gerken, T.A.,Hurtado-Guerrero, R. The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences. Nat Commun, 8:1959-1959, 2017 Cited by PubMed: 29208955DOI: 10.1038/s41467-017-02006-0 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
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