5NQA

Crystal structure of GalNAc-T4 in complex with the monoglycopeptide 3

Summary for 5NQA

• Entry DOI: 10.2210/pdb5nqa/pdb
• Descriptor: Polypeptide N-acetylgalactosaminyltransferase 4, Monoglycopeptide 3, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: galnac-t4, galnac-t2, chimeras, glycosylation preferences, std-nmr, flexible linker, transferase
• Biological source: Homo sapiens (Human); More
• Cellular location: Golgi apparatus membrane ; Single-pass type II membrane protein : Q8N4A0
• Total number of polymer chains: 3
• Total formula weight: 140480.98

Authors

de las Rivas, M.,Lira-Navarrete, E.,Daniel, E.J.P.,Companon, I.,Coelho, H.,Diniz, A.,Jimenez-Barbero, J.,Peregrina, J.M.,Clausen, H.,Corzana, F.,Marcelo, F.,Jimenez-Oses, G.,Gerken, T.A.,Hurtado-Guerrero, R. (deposition date: 2017-04-19, release date: 2017-12-20, Last modification date: 2024-01-17)

• Primary citation: Rivas, M.L.,Lira-Navarrete, E.,Daniel, E.J.P.,Companon, I.,Coelho, H.,Diniz, A.,Jimenez-Barbero, J.,Peregrina, J.M.,Clausen, H.,Corzana, F.,Marcelo, F.,Jimenez-Oses, G.,Gerken, T.A.,Hurtado-Guerrero, R.; The interdomain flexible linker of the polypeptide GalNAc transferases dictates their long-range glycosylation preferences.; Nat Commun, 8:1959-1959, 2017; PubMed: 29208955; DOI: 10.1038/s41467-017-02006-0

Experimental method

X-RAY DIFFRACTION (1.9 Å)