5NN1
The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1)
Summary for 5NN1
Entry DOI | 10.2210/pdb5nn1/pdb |
Descriptor | Serine/threonine-protein kinase PLK1 (2 entities in total) |
Functional Keywords | plk1, pbd1, mitosis, transferase |
Biological source | Homo sapiens (Human) |
Cellular location | Nucleus: P53350 |
Total number of polymer chains | 1 |
Total formula weight | 27285.16 |
Authors | Kunciw, D.L.,Rossmann, M.,De Fusco, C.,Spring, D.R.,Hyvonen, M. (deposition date: 2017-04-07, release date: 2018-02-21, Last modification date: 2024-06-19) |
Primary citation | Kunciw, D.L.,De Fusco, C.,Rossmann, M.,De Andres, M.,Sore, H.F.,Hyvonen, M.,Spring, D.R. Developing peptidic inhibitors of the cryptic pocket of the Polo-Like Kinase 1 Polo-Box Domain. To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.785 Å) |
Structure validation
Download full validation report