5NHG

Crystal structure of the human dihydrolipoamide dehydrogenase

5NHG の概要

• エントリーDOI: 10.2210/pdb5nhg/pdb
• 分子名称: Dihydrolipoyl dehydrogenase, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ... (5 entities in total)
• 機能のキーワード: dihydrolipoamide dehydrogenase, e3 subunit, oxidoreductase, pyruvate dehydrogenase complex, alpha-ketoglutarate dehydrogenase complex
• 由来する生物種: Homo sapiens (Human)
• タンパク質・核酸の鎖数: 8
• 化学式量合計: 427396.48

構造登録者

Szabo, E.,Mizsei, R.,Wilk, P.,Zambo, Z.,Torocsik, B.,Weiss, M.S.,Adam-Vizi, V.,Ambrus, A. (登録日: 2017-03-21, 公開日: 2018-05-16, 最終更新日: 2024-01-17)

• 主引用文献: Szabo, E.,Mizsei, R.,Wilk, P.,Zambo, Z.,Torocsik, B.,Weiss, M.S.,Adam-Vizi, V.,Ambrus, A.; Crystal structures of the disease-causing D444V mutant and the relevant wild type human dihydrolipoamide dehydrogenase.; Free Radic. Biol. Med., 124:214-220, 2018; PubMed: 29908278; DOI: 10.1016/j.freeradbiomed.2018.06.008

実験手法

X-RAY DIFFRACTION (2.27 Å)