5NF6

Structure of GluK3 ligand-binding domain (S1S2) in complex with CIP-AS at 2.55 A resolution

5NF6 の概要

• エントリーDOI: 10.2210/pdb5nf6/pdb
• 分子名称: Glutamate receptor ionotropic, kainate 3,Glutamate receptor ionotropic, kainate 3, ZINC ION, (3~{a}~{S},4~{S},6~{a}~{R})-4,5,6,6~{a}-tetrahydro-3~{a}~{H}-pyrrolo[3,4-d][1,2]oxazole-3,4-dicarboxylic acid, ... (7 entities in total)
• 機能のキーワード: ionotropic glutamate receptor, kainate receptor, ligand-binding domain, gluk3, glur7, agonist, membrane protein
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P42264
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 59256.34

構造登録者

Frydenvang, K.,Venskutonyte, R.,Thorsen, T.S.,Kastrup, J.S. (登録日: 2017-03-13, 公開日: 2017-07-26, 最終更新日: 2024-01-17)

• 主引用文献: Mllerud, S.,Pinto, A.,Marconi, L.,Frydenvang, K.,Thorsen, T.S.,Laulumaa, S.,Venskutonyte, R.,Winther, S.,Moral, A.M.C.,Tamborini, L.,Conti, P.,Pickering, D.S.,Kastrup, J.S.; Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.; ACS Chem Neurosci, 8:2056-2064, 2017; PubMed: 28691798; DOI: 10.1021/acschemneuro.7b00201

実験手法

X-RAY DIFFRACTION (2.55 Å)