5NEB

Structure of GluK1 ligand-binding domain (S1S2) in complex with LM-12b at 2.05 A resolution

5NEB の概要

• エントリーDOI: 10.2210/pdb5neb/pdb
• 分子名称: Glutamate receptor ionotropic, kainate 1, SULFATE ION, CHLORIDE ION, ... (7 entities in total)
• 機能のキーワード: ionotropic glutamate receptor, kainate receptor, ligand-binding domain, gluk1, glur5, agonist, membrane protein
• 由来する生物種: Rattus norvegicus (Rat); 詳細
• 細胞内の位置: Cell membrane; Multi-pass membrane protein: P22756
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 59796.84

構造登録者

Moellerud, S.,Frydenvang, K.,Laulumaa, S.,Kastrup, J.S. (登録日: 2017-03-10, 公開日: 2017-07-26, 最終更新日: 2024-01-17)

• 主引用文献: Mllerud, S.,Pinto, A.,Marconi, L.,Frydenvang, K.,Thorsen, T.S.,Laulumaa, S.,Venskutonyte, R.,Winther, S.,Moral, A.M.C.,Tamborini, L.,Conti, P.,Pickering, D.S.,Kastrup, J.S.; Structure and Affinity of Two Bicyclic Glutamate Analogues at AMPA and Kainate Receptors.; ACS Chem Neurosci, 8:2056-2064, 2017; PubMed: 28691798; DOI: 10.1021/acschemneuro.7b00201

実験手法

X-RAY DIFFRACTION (2.05 Å)