5NCJ

GriE in complex with manganese, succinate and (2S,4R)-5-hydroxyleucine

5NCJ の概要

• エントリーDOI: 10.2210/pdb5ncj/pdb
• 分子名称: Leucine hydroxylase, MANGANESE (II) ION, SUCCINIC ACID, ... (5 entities in total)
• 機能のキーワード: fe(ii)/alpha-ketoglutarate dependent dioxygenase, hydroxylase, non-heme iron protein, leucine hydroxylase, 5-hydroxyleucine, (2s4r)-5-hydroxyleucine, 4-methyl-proline, griselimycin, methyl-griselimycin, oxidoreductase
• 由来する生物種: Streptomyces sp. DSM 40835
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 60369.38

構造登録者

Lukat, P.,Blankenfeldt, W.,Mueller, R. (登録日: 2017-03-05, 公開日: 2017-10-04, 最終更新日: 2024-01-17)

• 主引用文献: Lukat, P.,Katsuyama, Y.,Wenzel, S.,Binz, T.,Konig, C.,Blankenfeldt, W.,Bronstrup, M.,Muller, R.; Biosynthesis of methyl-proline containing griselimycins, natural products with anti-tuberculosis activity.; Chem Sci, 8:7521-7527, 2017; PubMed: 29163906; DOI: 10.1039/c7sc02622f

実験手法

X-RAY DIFFRACTION (1.529 Å)