5NAH

Pseudomonas fluorescens kynurenine 3-monooxygenase (KMO) in complex with 3-{5-chloro-6-[(1R)-1-(6-methylpyridazin-3-yl)ethoxy]-1,2-benzoxazol-3-yl}propanoic acid

Summary for 5NAH

Entry DOI	10.2210/pdb5nah/pdb
Descriptor	Kynurenine 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, 3-[5-chloranyl-6-[(1~{R})-1-(6-methylpyridazin-3-yl)ethoxy]-1,2-benzoxazol-3-yl]propanoic acid, ... (4 entities in total)
Functional Keywords	kmo, oxidoreductase
Biological source	Pseudomonas fluorescens
Total number of polymer chains	2
Total formula weight	103869.69
Authors	Rowland, P. (deposition date: 2017-02-27, release date: 2017-06-21, Last modification date: 2017-07-19)
Primary citation	Hutchinson, J.P.,Rowland, P.,Taylor, M.R.D.,Christodoulou, E.M.,Haslam, C.,Hobbs, C.I.,Holmes, D.S.,Homes, P.,Liddle, J.,Mole, D.J.,Uings, I.,Walker, A.L.,Webster, S.P.,Mowat, C.G.,Chung, C.W. Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase. Nat Commun, 8:15827-15827, 2017 Cited by PubMed: 28604669 DOI: 10.1038/ncomms15827 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.75 Å)

Structure validation