5NAF
Co-crystal structure of an MeCP2 peptide with TBLR1 WD40 domain
Summary for 5NAF
Entry DOI | 10.2210/pdb5naf/pdb |
Descriptor | F-box-like/WD repeat-containing protein TBL1XR1, Methyl-CpG-binding protein 2, GLYCEROL, ... (4 entities in total) |
Functional Keywords | wd40 domain ; protein-peptide complex; transcriptional repressor; rett syndrome, transcription |
Biological source | Mus musculus (Mouse) More |
Cellular location | Nucleus : Q8BHJ5 Q9Z2D6 |
Total number of polymer chains | 6 |
Total formula weight | 183227.82 |
Authors | Kruusvee, V.,Cook, A.G. (deposition date: 2017-02-27, release date: 2017-03-29, Last modification date: 2024-01-17) |
Primary citation | Kruusvee, V.,Lyst, M.J.,Taylor, C.,Tarnauskaite, Z.,Bird, A.P.,Cook, A.G. Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders. Proc. Natl. Acad. Sci. U.S.A., 114:E3243-E3250, 2017 Cited by PubMed: 28348241DOI: 10.1073/pnas.1700731114 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.493 Å) |
Structure validation
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