5NAB

Pseudomonas fluorescens kynurenine 3-monooxygenase (KMO) in complex with 3-(5-chloro-6-methyl-2-oxo-2,3-dihydro-1,3-benzoxazol-3-yl)propanoic acid

Summary for 5NAB

• Entry DOI: 10.2210/pdb5nab/pdb
• Descriptor: Kynurenine 3-monooxygenase, FLAVIN-ADENINE DINUCLEOTIDE, CHLORIDE ION, ... (6 entities in total)
• Functional Keywords: kmo, oxidoreductase
• Biological source: Pseudomonas fluorescens
• Total number of polymer chains: 2
• Total formula weight: 104369.11

Authors

Rowland, P. (deposition date: 2017-02-27, release date: 2017-06-21)

• Primary citation: Hutchinson, J.P.,Rowland, P.,Taylor, M.R.D.,Christodoulou, E.M.,Haslam, C.,Hobbs, C.I.,Holmes, D.S.,Homes, P.,Liddle, J.,Mole, D.J.,Uings, I.,Walker, A.L.,Webster, S.P.,Mowat, C.G.,Chung, C.W.; Structural and mechanistic basis of differentiated inhibitors of the acute pancreatitis target kynurenine-3-monooxygenase.; Nat Commun, 8:15827-15827, 2017; PubMed: 28604669; DOI: 10.1038/ncomms15827

Experimental method

X-RAY DIFFRACTION (1.63 Å)