Structure of adenylation domain THR1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces SP.OH-5093, ligand bound structure

Replaces:  5APB

Summary for 5N9X

DescriptorAdenylation domain, THREONINE, ADENOSINE-5'-TRIPHOSPHATE, ... (6 entities in total)
Functional Keywordsadenylation domain, substrate specificity, non-ribosomal code, threonine adenylate, ligase
Biological sourceStreptomyces sp.
Total number of polymer chains2
Total molecular weight116548.81
Savino, C.,Vallone, B.,Scaglione, A.,Parisi, G.,Montemiglio, L.C.,Fullone, M.R.,Grgurina, I. (deposition date: 2017-02-27, release date: 2017-07-26, Last modification date: 2017-09-27)
Primary citation
Scaglione, A.,Fullone, M.R.,Montemiglio, L.C.,Parisi, G.,Zamparelli, C.,Vallone, B.,Savino, C.,Grgurina, I.
Structure of the adenylation domain Thr1 involved in the biosynthesis of 4-chlorothreonine in Streptomyces sp. OH-5093-protein flexibility and molecular bases of substrate specificity.
FEBS J., 284:2981-2999, 2017
PubMed: 28704585 (PDB entries with the same primary citation)
DOI: 10.1111/febs.14163
MImport into Mendeley
Experimental method

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.275903.2%3.3%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation reportDownload
PDB entries from 2020-08-05