5N6S
Thermotoga maritima family 1 Glycoside hydrolase complexed with Carba-Cyclophellitol transition state mimic
Summary for 5N6S
Entry DOI | 10.2210/pdb5n6s/pdb |
Descriptor | Beta-glucosidase A, 1,2-ETHANEDIOL, CHLORIDE ION, ... (9 entities in total) |
Functional Keywords | hydrolase, carba-cyclophellitol, mimic |
Biological source | Thermotoga maritima |
Total number of polymer chains | 4 |
Total formula weight | 218903.50 |
Authors | Offen, W.,Davies, G. (deposition date: 2017-02-16, release date: 2017-03-01, Last modification date: 2024-01-17) |
Primary citation | Beenakker, T.J.M.,Wander, D.P.A.,Offen, W.A.,Artola, M.,Raich, L.,Ferraz, M.J.,Li, K.Y.,Houben, J.H.P.M.,van Rijssel, E.R.,Hansen, T.,van der Marel, G.A.,Codee, J.D.C.,Aerts, J.M.F.G.,Rovira, C.,Davies, G.J.,Overkleeft, H.S. Carba-cyclophellitols Are Neutral Retaining-Glucosidase Inhibitors. J. Am. Chem. Soc., 139:6534-6537, 2017 Cited by PubMed: 28463498DOI: 10.1021/jacs.7b01773 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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