5N6O

Wild type human Rac1-GDP

Summary for 5N6O

• Entry DOI: 10.2210/pdb5n6o/pdb
• Descriptor: Ras-related C3 botulinum toxin substrate 1, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: rac, gtpase, gdp, guanine exchange factor, gef, protein binding
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 2
• Total formula weight: 40094.15

Authors

Cherfils, J.,Ferrandez, Y. (deposition date: 2017-02-15, release date: 2017-12-27, Last modification date: 2020-11-18)

• Primary citation: Ferrandez, Y.,Zhang, W.,Peurois, F.,Akendengue, L.,Blangy, A.,Zeghouf, M.,Cherfils, J.; Allosteric inhibition of the guanine nucleotide exchange factor DOCK5 by a small molecule.; Sci Rep, 7:14409-14409, 2017; PubMed: 29089502; DOI: 10.1038/s41598-017-13619-2

Experimental method

X-RAY DIFFRACTION (2.59 Å)