5N6F
Crystal structure of TGT in complex with guanine fragment
Summary for 5N6F
Entry DOI | 10.2210/pdb5n6f/pdb |
Descriptor | Queuine tRNA-ribosyltransferase, ZINC ION, DIMETHYL SULFOXIDE, ... (7 entities in total) |
Functional Keywords | tgt, trna, guanine exchange enzyme, transglycosylase, transferase |
Biological source | Zymomonas mobilis subsp. mobilis (strain ATCC 31821 / ZM4 / CP4) |
Total number of polymer chains | 1 |
Total formula weight | 42314.44 |
Authors | Hassaan, E.,Heine, A.,Klebe, G. (deposition date: 2017-02-15, release date: 2018-03-07, Last modification date: 2024-01-17) |
Primary citation | Hassaan, E.,Eriksson, P.O.,Geschwindner, S.,Heine, A.,Klebe, G. Fragments as Novel Starting Points for tRNA-Guanine Transglycosylase Inhibitors Found by Alternative Screening Strategies. Chemmedchem, 15:324-337, 2020 Cited by PubMed: 31808981DOI: 10.1002/cmdc.201900604 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.11909520042 Å) |
Structure validation
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