5N6A
Cardiac muscle myosin motor domain in the pre-powerstroke state
Summary for 5N6A
Entry DOI | 10.2210/pdb5n6a/pdb |
Descriptor | Myosin-7, ADENOSINE-5'-DIPHOSPHATE, PHOSPHATE ION, ... (6 entities in total) |
Functional Keywords | myosin, cardiac, pre-powerstroke, motor protein |
Biological source | Bos taurus (cattle) |
Cellular location | Cytoplasm, myofibril : Q9BE39 |
Total number of polymer chains | 1 |
Total formula weight | 95431.23 |
Authors | Planelles-Herrero, V.J.,Hartman, J.J.,Robert-Paganin, J.,Malik, F.I.,Houdusse, A. (deposition date: 2017-02-14, release date: 2017-08-09, Last modification date: 2024-01-17) |
Primary citation | Planelles-Herrero, V.J.,Hartman, J.J.,Robert-Paganin, J.,Malik, F.I.,Houdusse, A. Mechanistic and structural basis for activation of cardiac myosin force production by omecamtiv mecarbil. Nat Commun, 8:190-190, 2017 Cited by PubMed: 28775348DOI: 10.1038/s41467-017-00176-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.1 Å) |
Structure validation
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