5N30

Crystal structure of the V72I mutant of the mouse alpha-Dystroglycan N-terminal region

Summary for 5N30

Entry DOI	10.2210/pdb5n30/pdb
Descriptor	Dystroglycan, 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, ... (4 entities in total)
Functional Keywords	dystroglycan cell adhesion laminin binding, cell adhesion
Biological source	Mus musculus (House Mouse)
Cellular location	Alpha-dystroglycan: Secreted, extracellular space . Beta-dystroglycan: Cell membrane ; Single-pass type I membrane protein : Q62165
Total number of polymer chains	1
Total formula weight	28604.56
Authors	Cassetta, A.,Covaceuszach, S.,Brancaccio, A.,Sciandra, F.,Bozzi, M.,Bigotti, M.G.,Konarev, P.V. (deposition date: 2017-02-08, release date: 2017-11-01, Last modification date: 2024-01-17)
Primary citation	Covaceuszach, S.,Bozzi, M.,Bigotti, M.G.,Sciandra, F.,Konarev, P.V.,Brancaccio, A.,Cassetta, A. The effect of the pathological V72I, D109N and T190M missense mutations on the molecular structure of alpha-dystroglycan. PLoS ONE, 12:e0186110-e0186110, 2017 Cited by PubMed: 29036200 DOI: 10.1371/journal.pone.0186110 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.8 Å)

Structure validation