5N2L
Crystal structure of the second bromodomain of human BRD2 in complex with a tetrahydroquinoline analogue
Summary for 5N2L
Entry DOI | 10.2210/pdb5n2l/pdb |
Descriptor | Bromodomain-containing protein 2, SULFATE ION, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | transcription, structural genomics, structural genomics consortium, sgc |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 4 |
Total formula weight | 56020.31 |
Authors | Tallant, C.,Slavish, P.J.,Siejka, P.,Bharatham, N.,Shadrick, W.R.,Chai, S.,Young, B.M.,Boyd, V.A.,Heroven, C.,Wiggers, H.J.,Picaud, S.,Fedorov, O.,Krojer, T.,Chen, T.,Lee, R.E.,Guy, R.K.,Shelat, A.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (deposition date: 2017-02-07, release date: 2018-02-28, Last modification date: 2024-01-17) |
Primary citation | Tallant, C.,Slavish, P.J.,Siejka, P.,Bharatham, N.,Shadrick, W.R.,Chai, S.,Young, B.M.,Boyd, V.A.,Heroven, C.,Wiggers, H.J.,Picaud, S.,Fedorov, O.,Krojer, T.,Chen, T.,Lee, R.E.,Guy, R.K.,Shelat, A.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S. Crystal structure of the second bromodomain of human BRD2 in complex with a tetrahydroquinoline analogue To Be Published, |
Experimental method | X-RAY DIFFRACTION (1.89 Å) |
Structure validation
Download full validation report