5N2L
Crystal structure of the second bromodomain of human BRD2 in complex with a tetrahydroquinoline analogue
5N2L の概要
エントリーDOI | 10.2210/pdb5n2l/pdb |
分子名称 | Bromodomain-containing protein 2, SULFATE ION, 1,2-ETHANEDIOL, ... (5 entities in total) |
機能のキーワード | transcription, structural genomics, structural genomics consortium, sgc |
由来する生物種 | Homo sapiens (Human) |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 56020.31 |
構造登録者 | Tallant, C.,Slavish, P.J.,Siejka, P.,Bharatham, N.,Shadrick, W.R.,Chai, S.,Young, B.M.,Boyd, V.A.,Heroven, C.,Wiggers, H.J.,Picaud, S.,Fedorov, O.,Krojer, T.,Chen, T.,Lee, R.E.,Guy, R.K.,Shelat, A.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S.,Structural Genomics Consortium (SGC) (登録日: 2017-02-07, 公開日: 2018-02-28, 最終更新日: 2024-01-17) |
主引用文献 | Tallant, C.,Slavish, P.J.,Siejka, P.,Bharatham, N.,Shadrick, W.R.,Chai, S.,Young, B.M.,Boyd, V.A.,Heroven, C.,Wiggers, H.J.,Picaud, S.,Fedorov, O.,Krojer, T.,Chen, T.,Lee, R.E.,Guy, R.K.,Shelat, A.A.,von Delft, F.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Knapp, S. Crystal structure of the second bromodomain of human BRD2 in complex with a tetrahydroquinoline analogue To Be Published, |
実験手法 | X-RAY DIFFRACTION (1.89 Å) |
構造検証レポート
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