5N23

Protein kinase A mutants as surrogate model for Aurora B with AT9283 inhibitor

5N23 の概要

• エントリーDOI: 10.2210/pdb5n23/pdb
• 分子名称: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, 1-cyclopropyl-3-{3-[5-(morpholin-4-ylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl}urea, ... (4 entities in total)
• 機能のキーワード: at9283, surrogate kinase, transferase
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Cytoplasm. Isoform 2: Cell projection, cilium, flagellum : P17612
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 43641.40

構造登録者

Alam, K.A.,Rothweiler, U.,Engh, R.A. (登録日: 2017-02-07, 公開日: 2018-03-14, 最終更新日: 2024-01-17)

• 主引用文献: Alam, K.A.,Engh, R.A.; Inhibitor induced structural effects involving Phe327 in AGC kinases; To Be Published,

実験手法

X-RAY DIFFRACTION (2.088 Å)