5N0Y

hPAD4 crystal complex with AFM-30a

Summary for 5N0Y

• Entry DOI: 10.2210/pdb5n0y/pdb
• Related: 5N0M
• Descriptor: Protein-arginine deiminase type-4, SULFATE ION, CALCIUM ION, ... (5 entities in total)
• Functional Keywords: hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (Human)
• Cellular location: Cytoplasm: Q9UM07
• Total number of polymer chains: 1
• Total formula weight: 75676.77

Authors

Beaumont, E.,Kerry, P.,Thompson, P.,Muth, A.,Subramanian, V.,Nagar, M.,Srinath, H.,Clancy, K.,Parelkar, S. (deposition date: 2017-02-03, release date: 2017-05-24)

• Primary citation: Muth, A.,Subramanian, V.,Beaumont, E.,Nagar, M.,Kerry, P.,McEwan, P.,Srinath, H.,Clancy, K.,Parelkar, S.,Thompson, P.R.; Development of a Selective Inhibitor of Protein Arginine Deiminase 2.; J. Med. Chem., 60:3198-3211, 2017; PubMed: 28328217; DOI: 10.1021/acs.jmedchem.7b00274

Experimental method

X-RAY DIFFRACTION (2.23 Å)