5MZL

Crystal structure of human Pim-1 kinase in complex with a consensuspeptide and fragment like molekule N-quinolin-5-ylpyridine-3-carboxamide

Summary for 5MZL

• Entry DOI: 10.2210/pdb5mzl/pdb
• Descriptor: Serine/threonine-protein kinase pim-1, Pimtide, ~{N}-quinolin-5-ylpyridine-3-carboxamide, ... (5 entities in total)
• Functional Keywords: serine threonine kinase, transferase, proto-oncogene, fragment, pim-1, consensus peptide
• Biological source: Homo sapiens (Human); More
• Cellular location: Isoform 2: Cytoplasm. Isoform 1: Cell membrane: P11309
• Total number of polymer chains: 2
• Total formula weight: 37566.81

Authors

Siefker, C.,Heine, A.,Klebe, G. (deposition date: 2017-02-01, release date: 2018-02-14, Last modification date: 2024-01-17)

• Primary citation: Siefker, C.,Heine, A.,Hardes, K.,Steinmetzer, A.,Klebe, G.; A crystallographic fragment study with human Pim-1 kinase; to be published,

Experimental method

X-RAY DIFFRACTION (1.955 Å)