5MYA

Homodimerization of Tie2 Fibronectin-like domains 1-3 in space group C2

5MYA の概要

• エントリーDOI: 10.2210/pdb5mya/pdb
• 分子名称: Angiopoietin-1 receptor, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: receptor, fibronectin-like domains, dimerization, homotypic interactions, signaling protein
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein: Q02763
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 77811.08

構造登録者

Leppanen, V.-M.,Saharinen, P.,Alitalo, K. (登録日: 2017-01-26, 公開日: 2017-04-26, 最終更新日: 2020-07-29)

• 主引用文献: Leppanen, V.M.,Saharinen, P.,Alitalo, K.; Structural basis of Tie2 activation and Tie2/Tie1 heterodimerization.; Proc. Natl. Acad. Sci. U.S.A., 114:4376-4381, 2017; PubMed: 28396439; DOI: 10.1073/pnas.1616166114

実験手法

X-RAY DIFFRACTION (2.9 Å)