5MVF

Active structure of EHD4 complexed with ADP

Summary for 5MVF

• Entry DOI: 10.2210/pdb5mvf/pdb
• Related: 5MTV
• Descriptor: EH domain-containing protein 4, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: dynamin-like, auto-inhibition, activation, endocytosis
• Biological source: Mus musculus (Mouse)
• Cellular location: Early endosome membrane ; Peripheral membrane protein ; Cytoplasmic side : Q9EQP2
• Total number of polymer chains: 1
• Total formula weight: 59939.58

Authors

Melo, A.A.,Daumke, O. (deposition date: 2017-01-16, release date: 2017-03-08, Last modification date: 2024-01-17)

• Primary citation: Melo, A.A.,Hegde, B.G.,Shah, C.,Larsson, E.,Isas, J.M.,Kunz, S.,Lundmark, R.,Langen, R.,Daumke, O.; Structural insights into the activation mechanism of dynamin-like EHD ATPases.; Proc. Natl. Acad. Sci. U.S.A., 114:5629-5634, 2017; PubMed: 28228524; DOI: 10.1073/pnas.1614075114

Experimental method

X-RAY DIFFRACTION (3.268 Å)