5MUR

X-ray structure of the F14'A mutant of GLIC in complex with propofol

Summary for 5MUR

Entry DOI	10.2210/pdb5mur/pdb
Descriptor	Proton-gated ion channel, ACETATE ION, CHLORIDE ION, ... (7 entities in total)
Functional Keywords	membrane protein, transport protein
Biological source	Gloeobacter violaceus (strain PCC 7421)
Total number of polymer chains	5
Total formula weight	185384.48
Authors	Sauguet, L.,Fourati, Z.,Delarue, M. (deposition date: 2017-01-13, release date: 2018-02-14, Last modification date: 2024-01-17)
Primary citation	Fourati, Z.,Howard, R.J.,Heusser, S.A.,Hu, H.,Ruza, R.R.,Sauguet, L.,Lindahl, E.,Delarue, M. Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels. Cell Rep, 23:993-1004, 2018 Cited by PubMed: 29694907 DOI: 10.1016/j.celrep.2018.03.108 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (3.1 Å)

Structure validation