5MUO
X-ray structure of the 2-22' locally-closed mutant of GLIC in complex with propofol
Summary for 5MUO
Entry DOI | 10.2210/pdb5muo/pdb |
Related | 3TLS 3TLT 3TLU 3TLW |
Descriptor | Proton-gated ion channel, DODECYL-BETA-D-MALTOSIDE, CHLORIDE ION, ... (6 entities in total) |
Functional Keywords | membrane protein, transport protein |
Biological source | Gloeobacter violaceus |
Total number of polymer chains | 5 |
Total formula weight | 183731.94 |
Authors | Fourati, Z.,Ruza, R.R.,Delarue, M. (deposition date: 2017-01-13, release date: 2018-02-14, Last modification date: 2024-01-17) |
Primary citation | Fourati, Z.,Howard, R.J.,Heusser, S.A.,Hu, H.,Ruza, R.R.,Sauguet, L.,Lindahl, E.,Delarue, M. Structural Basis for a Bimodal Allosteric Mechanism of General Anesthetic Modulation in Pentameric Ligand-Gated Ion Channels. Cell Rep, 23:993-1004, 2018 Cited by PubMed: 29694907DOI: 10.1016/j.celrep.2018.03.108 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.19 Å) |
Structure validation
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