5MUD
Crystal structure of an amyloidogenic light chain dimer H6
Summary for 5MUD
| Entry DOI | 10.2210/pdb5mud/pdb |
| Descriptor | light chain dimer,IGL@ protein (2 entities in total) |
| Functional Keywords | light chain dimer, light chain amyloidosis, immunoglobulin fold, protein aggregation, immune system |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 2 |
| Total formula weight | 45526.44 |
| Authors | Oberti, L.,Bacarizo, J.,Maritan, M.,Rognoni, P.,Bolognesi, M.,Ricagno, S. (deposition date: 2017-01-13, release date: 2017-12-13, Last modification date: 2024-01-17) |
| Primary citation | Oberti, L.,Rognoni, P.,Barbiroli, A.,Lavatelli, F.,Russo, R.,Maritan, M.,Palladini, G.,Bolognesi, M.,Merlini, G.,Ricagno, S. Concurrent structural and biophysical traits link with immunoglobulin light chains amyloid propensity. Sci Rep, 7:16809-16809, 2017 Cited by PubMed: 29196671DOI: 10.1038/s41598-017-16953-7 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2.34 Å) |
Structure validation
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