5MUC
Crystal structure of the FimH lectin domain in complex with 1,5-Anhydromannitol
Summary for 5MUC
Entry DOI | 10.2210/pdb5muc/pdb |
Descriptor | Protein FimH, 1-deoxy-alpha-D-mannopyranose (3 entities in total) |
Functional Keywords | fimh, uti, lectin, carbohydrate, upec, bladder infection, sugar binding protein |
Biological source | Escherichia coli (strain K12) |
Total number of polymer chains | 2 |
Total formula weight | 34161.97 |
Authors | Jakob, R.P.,Rabbani, S.,Ernst, B.,Maier, T. (deposition date: 2017-01-13, release date: 2018-02-14, Last modification date: 2024-01-17) |
Primary citation | Zihlmann, P.,Silbermann, M.,Sharpe, T.,Jiang, X.,Muhlethaler, T.,Jakob, R.P.,Rabbani, S.,Sager, C.P.,Frei, P.,Pang, L.,Maier, T.,Ernst, B. KinITC-One Method Supports both Thermodynamic and Kinetic SARs as Exemplified on FimH Antagonists. Chemistry, 24:13049-13057, 2018 Cited by PubMed: 29939458DOI: 10.1002/chem.201802599 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.6 Å) |
Structure validation
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