5MR4

Ligand-receptor complex.

Summary for 5MR4

• Entry DOI: 10.2210/pdb5mr4/pdb
• Related: 5MR4 5MR5 5NMZ
• Descriptor: Neurturin, GDNF family receptor alpha-2, DI(HYDROXYETHYL)ETHER, ... (5 entities in total)
• Functional Keywords: complex, signalling, receptor, signaling protein
• Biological source: Homo sapiens (Human); More
• Cellular location: Secreted: Q99748; Cell membrane ; Lipid-anchor, GPI-anchor : O00451
• Total number of polymer chains: 4
• Total formula weight: 125522.36

Authors

Sandmark, J.,Oster, L.,Aagaard, A.,Roth, R.G.,Dahl, G. (deposition date: 2016-12-21, release date: 2018-01-17, Last modification date: 2024-01-17)

• Primary citation: Sandmark, J.,Dahl, G.,Oster, L.,Xu, B.,Johansson, P.,Akerud, T.,Aagaard, A.,Davidsson, P.,Bigalke, J.M.,Winzell, M.S.,Rainey, G.J.,Roth, R.G.; Structure and biophysical characterization of the human full-length neurturin-GFRa2 complex: A role for heparan sulfate in signaling.; J. Biol. Chem., 293:5492-5508, 2018; PubMed: 29414779; DOI: 10.1074/jbc.RA117.000820

Experimental method

X-RAY DIFFRACTION (2.4 Å)