5MQ1

Crystal structure of the BRD7 bromodomain in complex with BI-9564

5MQ1 の概要

• エントリーDOI: 10.2210/pdb5mq1/pdb
• 分子名称: Bromodomain-containing protein 7, 4-[4-[(dimethylamino)methyl]-2,5-dimethoxy-phenyl]-2-methyl-2,7-naphthyridin-1-one, ZINC ION, ... (7 entities in total)
• 機能のキーワード: bromodomain, transcription
• 由来する生物種: Homo sapiens (Human)
• 細胞内の位置: Isoform 2: Nucleus: Q9NPI1
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 14472.92

構造登録者

Diaz-Saez, L.,Martin, L.J.,Panagakou, I.,Picaud, S.,Krojer, T.,von Delft, F.,Knapp, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.,Structural Genomics Consortium (SGC) (登録日: 2016-12-19, 公開日: 2018-01-17, 最終更新日: 2024-05-01)

• 主引用文献: Diaz-Saez, L.,Martin, L.J.,Panagakou, I.,Picaud, S.,Krojer, T.,von Delft, F.,Knapp, S.,Arrowsmith, C.H.,Edwards, A.M.,Bountra, C.,Huber, K.,Structural Genomics Consortium (SGC); Crystal structure of the BRD7 bromodomain in complex with BI-9564; To Be Published,

実験手法

X-RAY DIFFRACTION (1.5 Å)