5MPS
Structure of a spliceosome remodeled for exon ligation
Summary for 5MPS
Entry DOI | 10.2210/pdb5mps/pdb |
EMDB information | 3539 |
Descriptor | Yeast UBC4 gene for ubiquitin-conjugating enzyme, Pre-mRNA-processing protein 45, Pre-mRNA-splicing factor BUD31, ... (35 entities in total) |
Functional Keywords | pre-mrna splicing, trans-esterification, lariat intermediate, complex c-star, splicing |
Biological source | Saccharomyces cerevisiae (Baker's yeast) More |
Total number of polymer chains | 30 |
Total formula weight | 1696095.17 |
Authors | Fica, S.M.,Oubridge, C.,Galej, W.P.,Wilkinson, M.E.,Newman, A.J.,Bai, X.-C.,Nagai, K. (deposition date: 2016-12-18, release date: 2017-01-18, Last modification date: 2020-10-07) |
Primary citation | Fica, S.M.,Oubridge, C.,Galej, W.P.,Wilkinson, M.E.,Bai, X.C.,Newman, A.J.,Nagai, K. Structure of a spliceosome remodelled for exon ligation. Nature, 542:377-380, 2017 Cited by PubMed: 28076345DOI: 10.1038/nature21078 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (3.85 Å) |
Structure validation
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