5MPQ
Bulgecin A: The key to a broad-spectrum inhibitor that targets lytic transglycosylases
Summary for 5MPQ
Entry DOI | 10.2210/pdb5mpq/pdb |
Descriptor | Transglycosylase, 4-O-(4-O-SULFONYL-N-ACETYLGLUCOSAMININYL)-5-METHYLHYDROXY-L-PROLINE-TAURINE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | bulgecin a, ltga, lytic transglycosylase, peptidoglycan, lyase |
Biological source | Neisseria meningitidis |
Total number of polymer chains | 1 |
Total formula weight | 64535.00 |
Authors | Williams, A.H. (deposition date: 2016-12-17, release date: 2017-03-29, Last modification date: 2024-01-17) |
Primary citation | Williams, A.H.,Wheeler, R.,Thiriau, C.,Haouz, A.,Taha, M.K.,Boneca, I.G. Bulgecin A: The Key to a Broad-Spectrum Inhibitor That Targets Lytic Transglycosylases. Antibiotics, 6:-, 2017 Cited by PubMed: 28241458DOI: 10.3390/antibiotics6010008 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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