5MPQ

Bulgecin A: The key to a broad-spectrum inhibitor that targets lytic transglycosylases

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0042597	cellular_component	periplasmic space
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	16
Details	binding site for residue BLG A 601

Chain	Residue
A	GLU457
A	TYR527
A	ASN528
A	GLY530
A	GLU556
A	HOH811
A	HOH889
A	HOH908
A	SER466
A	ARG467
A	VAL468
A	ALA470
A	GLN475
A	MET477
A	THR480
A	TYR508

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site_id	AC2
Number of Residues	2
Details	binding site for residue MG A 602

Chain	Residue
A	GLN456
A	GLU457

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site_id	AC3
Number of Residues	2
Details	binding site for residue MG A 603

Chain	Residue
A	PRO553
A	SER555

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site_id	AC4
Number of Residues	9
Details	binding site for residue NHE A 604

Chain	Residue
A	PRO288
A	THR317
A	GLY318
A	ARG319
A	ASN320
A	GLU416
A	THR418
A	ARG427
A	HOH797

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