5MP6

Structure of the Unliganded Fab from HIV-1 Neutralizing Antibody CAP248-2B that Binds to the gp120 C-terminus - gp41 Interface, at two Angstrom resolution.

5MP6 の概要

• エントリーDOI: 10.2210/pdb5mp6/pdb
• 関連するPDBエントリー: 5F89
• 分子名称: CAP248-2B Heavy Chain, CAP248-2B Light Chain, SULFATE ION, ... (4 entities in total)
• 機能のキーワード: hiv, neutralizing antibody, gp120 c-terminus, cap248, gp120-gp41 interface, immune system
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 99906.55

構造登録者

Wibmer, C.K.,Gorman, J.,Kwong, P.D. (登録日: 2016-12-15, 公開日: 2016-12-28, 最終更新日: 2024-01-17)

• 主引用文献: Wibmer, C.K.,Gorman, J.,Ozorowski, G.,Bhiman, J.N.,Sheward, D.J.,Elliott, D.H.,Rouelle, J.,Smira, A.,Joyce, M.G.,Ndabambi, N.,Druz, A.,Asokan, M.,Burton, D.R.,Connors, M.,Abdool Karim, S.S.,Mascola, J.R.,Robinson, J.E.,Ward, A.B.,Williamson, C.,Kwong, P.D.,Morris, L.,Moore, P.L.; Structure and Recognition of a Novel HIV-1 gp120-gp41 Interface Antibody that Caused MPER Exposure through Viral Escape.; PLoS Pathog., 13:e1006074-e1006074, 2017; PubMed: 28076415; DOI: 10.1371/journal.ppat.1006074

実験手法

X-RAY DIFFRACTION (1.959 Å)