5MO0
Neutron structure of cationic trypsin in complex with benzamidine
Summary for 5MO0
Entry DOI | 10.2210/pdb5mo0/pdb |
Descriptor | Cationic trypsin, CALCIUM ION, BENZAMIDINE, ... (4 entities in total) |
Functional Keywords | hydrogen bonding, protonation, protein-ligand interaction, hydrolase |
Biological source | Bos taurus (Bovine) |
Total number of polymer chains | 1 |
Total formula weight | 23484.52 |
Authors | Schiebel, J.,Schrader, T.E.,Ostermann, A.,Heine, A.,Klebe, G. (deposition date: 2016-12-13, release date: 2018-02-28, Last modification date: 2024-01-17) |
Primary citation | Schiebel, J.,Gaspari, R.,Wulsdorf, T.,Ngo, K.,Sohn, C.,Schrader, T.E.,Cavalli, A.,Ostermann, A.,Heine, A.,Klebe, G. Intriguing role of water in protein-ligand binding studied by neutron crystallography on trypsin complexes. Nat Commun, 9:3559-3559, 2018 Cited by PubMed: 30177695DOI: 10.1038/s41467-018-05769-2 PDB entries with the same primary citation |
Experimental method | NEUTRON DIFFRACTION (1.502 Å) |
Structure validation
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