5MK1
Crystal structure of the His Domain Protein Tyrosine Phosphatase (HD-PTP/PTPN23) Bro1 domain (CHMP4A peptide complex structure)
Summary for 5MK1
Entry DOI | 10.2210/pdb5mk1/pdb |
Descriptor | Tyrosine-protein phosphatase non-receptor type 23, Charged multivesicular body protein 4a (3 entities in total) |
Functional Keywords | escrt-iii chmp4a, hydrolase |
Biological source | Homo sapiens (Human) More |
Cellular location | Nucleus: Q9H3S7 Cytoplasmic vesicle membrane: Q9BY43 |
Total number of polymer chains | 8 |
Total formula weight | 171232.84 |
Authors | Levy, C.,Gahloth, D. (deposition date: 2016-12-02, release date: 2017-08-16, Last modification date: 2024-01-17) |
Primary citation | Gahloth, D.,Levy, C.,Walker, L.,Wunderley, L.,Mould, A.P.,Taylor, S.,Woodman, P.,Tabernero, L. Structural Basis for Specific Interaction of TGF beta Signaling Regulators SARA/Endofin with HD-PTP. Structure, 25:1011-1024.e4, 2017 Cited by PubMed: 28602823DOI: 10.1016/j.str.2017.05.005 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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