5MJT
Thrombin Mutant A190S in complex with (S) -1 - ((R) -2-amino-3,3-diphenylpropanoyl) -N- (3-chlorobenzyl) pyrrolidine-2-carboxamide
Summary for 5MJT
Entry DOI | 10.2210/pdb5mjt/pdb |
Descriptor | Thrombin light chain, Thrombin heavy chain, Hirudin variant-2, ... (9 entities in total) |
Functional Keywords | coagulation, blood clotting, convertion of fibrinogen to fibrin, blood clotting inhibitor, preorganization, glycosilation, blood, hydrolase |
Biological source | Homo sapiens (Human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P09945 |
Total number of polymer chains | 3 |
Total formula weight | 36582.87 |
Authors | Marca, A.,Sandner, A.,Heine, A.,Klebe, G. (deposition date: 2016-12-01, release date: 2017-12-20, Last modification date: 2024-10-09) |
Primary citation | Marca, A.,Ngo, K.,Sandner, A.,Heine, A.,Klebe, G. Thrombin Mutant A190S in complex with (S) -1 - ((R) -2-amino-3,3-diphenylpropanoyl) -N- (3-chlorobenzyl) pyrrolidine-2-carboxamide to be published, |
Experimental method | X-RAY DIFFRACTION (1.4 Å) |
Structure validation
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