5MJT

Thrombin Mutant A190S in complex with (S) -1 - ((R) -2-amino-3,3-diphenylpropanoyl) -N- (3-chlorobenzyl) pyrrolidine-2-carboxamide

5MJT の概要

• エントリーDOI: 10.2210/pdb5mjt/pdb
• 分子名称: Thrombin light chain, Thrombin heavy chain, Hirudin variant-2, ... (9 entities in total)
• 機能のキーワード: coagulation, blood clotting, convertion of fibrinogen to fibrin, blood clotting inhibitor, preorganization, glycosilation, blood, hydrolase
• 由来する生物種: Homo sapiens (Human); 詳細
• 細胞内の位置: Secreted, extracellular space: P00734 P00734; Secreted: P09945
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 36582.87

構造登録者

Marca, A.,Sandner, A.,Heine, A.,Klebe, G. (登録日: 2016-12-01, 公開日: 2017-12-20)

• 主引用文献: Marca, A.,Ngo, K.,Sandner, A.,Heine, A.,Klebe, G.; Thrombin Mutant A190S in complex with (S) -1 - ((R) -2-amino-3,3-diphenylpropanoyl) -N- (3-chlorobenzyl) pyrrolidine-2-carboxamide; to be published,

実験手法

X-RAY DIFFRACTION (1.4 Å)