5MHJ

ICP4 DNA-binding domain, lacking intrinsically disordered region, in complex with 12mer DNA duplex from its own promoter

5MHJ の概要

• エントリーDOI: 10.2210/pdb5mhj/pdb
• 分子名称: Major viral transcription factor ICP4, DNA (5'-D(P*CP*GP*AP*TP*CP*GP*TP*CP*C)-3'), ACETIC ACID, ... (6 entities in total)
• 機能のキーワード: transcription factor, dimer, herpes, virus, transcription
• 由来する生物種: Human herpesvirus 1 (strain 17) (HHV-1); 詳細
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 50106.23

構造登録者

Tunnicliffe, R.B.,Lockhart-Cairns, M.P.,Levy, C.,Mould, P.,Jowitt, T.A.,Sito, H.,Baldock, C.,Sandri-Goldin, R.M.,Golovanov, A.P. (登録日: 2016-11-24, 公開日: 2017-05-24, 最終更新日: 2024-05-01)

• 主引用文献: Tunnicliffe, R.B.,Lockhart-Cairns, M.P.,Levy, C.,Mould, A.P.,Jowitt, T.A.,Sito, H.,Baldock, C.,Sandri-Goldin, R.M.,Golovanov, A.P.; The herpes viral transcription factor ICP4 forms a novel DNA recognition complex.; Nucleic Acids Res., 45:8064-8078, 2017; PubMed: 28505309; DOI: 10.1093/nar/gkx419

実験手法

X-RAY DIFFRACTION (2.117 Å)