5MFR
The crystal structure of E. coli Aminopeptidase N in complex with 7-amino-5,7,8,9-tetrahydrobenzocyclohepten-6-one
Summary for 5MFR
Entry DOI | 10.2210/pdb5mfr/pdb |
Descriptor | Aminopeptidase N, ZINC ION, [(7~{S})-6,6-bis(oxidanyl)-5,7,8,9-tetrahydrobenzo[7]annulen-7-yl]azanium, ... (9 entities in total) |
Functional Keywords | m1 aminopeptidase, hydrolase |
Biological source | Escherichia coli (strain K12) |
Cellular location | Cell inner membrane; Peripheral membrane protein; Cytoplasmic side: P04825 |
Total number of polymer chains | 1 |
Total formula weight | 103476.52 |
Authors | Peng, G.,Olieric, V.,McEwen, A.G.,Schmitt, C.,Albrecht, S.,Cavarelli, J.,Tarnus, C. (deposition date: 2016-11-18, release date: 2017-04-19, Last modification date: 2024-01-17) |
Primary citation | Peng, G.,McEwen, A.G.,Olieric, V.,Schmitt, C.,Albrecht, S.,Cavarelli, J.,Tarnus, C. Insight into the remarkable affinity and selectivity of the aminobenzosuberone scaffold for the M1 aminopeptidases family based on structure analysis. Proteins, 85:1413-1421, 2017 Cited by PubMed: 28383176DOI: 10.1002/prot.25301 PDB entries with the same primary citation |
Experimental method |
Structure validation
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