5MEM

A potent fluorescent inhibitor of glycogen phosphorylase as a catalytic site probe.

Summary for 5MEM

Entry DOI	10.2210/pdb5mem/pdb
Descriptor	Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, 2-[[1-[(2~{R},3~{R},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]-2-oxidanylidene-pyrimidin-4-yl]amino]-10~{H}-acridin-9-one, ... (4 entities in total)
Functional Keywords	gp inhibitors, glucopyranosyl cytosine acridine derivatives, electronic absorption spectra, fluorescence spectra, fluorescent protein
Biological source	Oryctolagus cuniculus (Rabbit)
Total number of polymer chains	1
Total formula weight	98135.98
Authors	Mamais, M.,Chrysina, E.D. (deposition date: 2016-11-15, release date: 2017-11-29)
Primary citation	Mamais, M.,Degli Esposti, A.,Kouloumoundra, V.,Gustavsson, T.,Monti, F.,Venturini, A.,Chrysina, E.D.,Markovitsi, D.,Gimisis, T. A New Potent Inhibitor of Glycogen Phosphorylase Reveals the Basicity of the Catalytic Site. Chemistry, 23:8800-8805, 2017 Cited by PubMed: 28493496 DOI: 10.1002/chem.201701591 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.78 Å)

Structure validation