5MCT

New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins (complex p53DBD-LHG1)

5MCT の概要

• エントリーDOI: 10.2210/pdb5mct/pdb
• 関連するPDBエントリー: 3KZ8 5MCU 5MCV 5MCW 5MF7 5MG7 6FJ5
• 分子名称: Cellular tumor antigen p53, DNA, ZINC ION, ... (6 entities in total)
• 機能のキーワード: transcription, p53, transcription factor, dna binding, dna recognition, hoogsteen base-pairing, isoguanine, 2-oxo-adenine, transcription regulation, apoptosis, biological rhythms, cell cycle, nucleus, tumor suppressor, antigen ny-co-13, phosphoprotein
• 由来する生物種: Homo sapiens (Human); 詳細
• タンパク質・核酸の鎖数: 3
• 化学式量合計: 52047.58

構造登録者

Golovenko, D.,Rozenberg, H.,Shakked, Z. (登録日: 2016-11-10, 公開日: 2018-06-13, 最終更新日: 2024-01-17)

• 主引用文献: Golovenko, D.,Brauning, B.,Vyas, P.,Haran, T.E.,Rozenberg, H.,Shakked, Z.; New Insights into the Role of DNA Shape on Its Recognition by p53 Proteins.; Structure, 26:1237-1250.e6, 2018; PubMed: 30057026; DOI: 10.1016/j.str.2018.06.006

実験手法

X-RAY DIFFRACTION (1.446 Å)