5MCB

Glycogen phosphorylase in complex with chlorogenic acid.

5MCB の概要

• エントリーDOI: 10.2210/pdb5mcb/pdb
• 分子名称: Glycogen phosphorylase, muscle form, PYRIDOXAL-5'-PHOSPHATE, Chlorogenic acid, ... (4 entities in total)
• 機能のキーワード: alpha and beta protein, transferase
• 由来する生物種: Oryctolagus cuniculus (Rabbit)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 95882.37

構造登録者

Leonidas, D.D.,Stravodimos, G.A.,Kyriakis, E.,Chatzileontiadou, D.S.M.,Kantsadi, A.L. (登録日: 2016-11-09, 公開日: 2017-09-20, 最終更新日: 2024-01-17)

主引用文献

Stravodimos, G.A.,Kantsadi, A.L.,Apostolou, A.,Kyriakis, E.,Kafaski-Kanelli, V.N.,Solovou, T.,Gatzona, P.,Liggri, P.G.V.,Theofanous, S.,Gorgogietas, V.A.,Kissa, A.,Psachoula, C.,Lemonakis, A.,Chatzileontiadou, D.S.M.,Psarra, A.G.,Skamnaki, V.T.,Haroutounian, S.A.,Leonidas, D.D.
Affinity Crystallography Reveals the Bioactive Compounds of Industrial Juicing Byproducts of Punica granatum for Glycogen Phosphorylase.
Curr Drug Discov Technol, 15:41-53, 2018

PubMed Abstract: Glycogen phosphorylase (GP) is a pharmaceutical target for the discovery of new antihyperglycaemic agents. Punica granatum is a well-known plant for its potent antioxidant and antimicrobial activities but so far has not been examined for antihyperglycaemic activity.

PubMed: 28625148
DOI: 10.2174/1570163814666170619091736

実験手法

X-RAY DIFFRACTION (1.95 Å)