5M7R

Structure of human O-GlcNAc hydrolase

Summary for 5M7R

Entry DOI	10.2210/pdb5m7r/pdb
Descriptor	Protein O-GlcNAcase (2 entities in total)
Functional Keywords	human glacoside hydrolase glcnac, hydrolase
Biological source	Homo sapiens (Human)
Cellular location	Isoform 3: Nucleus . Isoform 1: Cytoplasm : O60502
Total number of polymer chains	2
Total formula weight	206041.81
Authors	Roth, C.,Chan, S.,Offen, W.A.,Hemsworth, G.R.,Willems, L.I.,King, D.,Varghese, V.,Britton, R.,Vocadlo, D.J.,Davies, G.J. (deposition date: 2016-10-28, release date: 2017-03-29, Last modification date: 2024-01-17)
Primary citation	Roth, C.,Chan, S.,Offen, W.A.,Hemsworth, G.R.,Willems, L.I.,King, D.T.,Varghese, V.,Britton, R.,Vocadlo, D.J.,Davies, G.J. Structural and functional insight into human O-GlcNAcase. Nat. Chem. Biol., 13:610-612, 2017 Cited by PubMed: 28346405 DOI: 10.1038/nchembio.2358 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.35 Å)

Structure validation