5M78
Human Carbonic Anhydrase II in complex with fragment-like inhibitor.
Summary for 5M78
Entry DOI | 10.2210/pdb5m78/pdb |
Descriptor | Carbonic anhydrase 2, DIMETHYL SULFOXIDE, ZINC ION, ... (6 entities in total) |
Functional Keywords | protein-ligand-complex, lyase |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 30409.95 |
Authors | Gloeckner, S.,Heine, A.,Klebe, G. (deposition date: 2016-10-27, release date: 2017-12-20, Last modification date: 2024-01-17) |
Primary citation | Glockner, S.,Heine, A.,Klebe, G. A Proof-of-Concept Fragment Screening of a Hit-Validated 96-Compounds Library against Human Carbonic Anhydrase II. Biomolecules, 10:-, 2020 Cited by PubMed: 32235320DOI: 10.3390/biom10040518 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.077 Å) |
Structure validation
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