5M6Z
The X-ray structure of human M189I PGK-1 mutant in partially closed conformation
Summary for 5M6Z
Entry DOI | 10.2210/pdb5m6z/pdb |
Descriptor | Phosphoglycerate kinase 1, 3-PHOSPHOGLYCERIC ACID, PHOSPHATE ION, ... (6 entities in total) |
Functional Keywords | transferase, human phosphoglycerate kinase 1, m189i snp -derived mutant |
Biological source | Homo sapiens (Human) |
Total number of polymer chains | 1 |
Total formula weight | 45280.23 |
Authors | Ilari, A.,Fiorillo, A.,Petrosino, M.,Cipollone, A. (deposition date: 2016-10-26, release date: 2017-11-29, Last modification date: 2024-01-17) |
Primary citation | Fiorillo, A.,Petrosino, M.,Ilari, A.,Pasquo, A.,Cipollone, A.,Maggi, M.,Chiaraluce, R.,Consalvi, V. The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme. PLoS ONE, 13:e0199191-e0199191, 2018 Cited by PubMed: 29995887DOI: 10.1371/journal.pone.0199191 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.67 Å) |
Structure validation
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