5M4W
Structure of DNA AGCGA-quadruplex adopted by 15-mer oligonucleotide found in regulatory region of the PLEKHG3 human gene with G11 to I11 mutation, d(GCGAGGGAGCIAGGG),VK34_I11
Summary for 5M4W
Entry DOI | 10.2210/pdb5m4w/pdb |
NMR Information | BMRB: 34056 |
Descriptor | DNA (5'-D(*GP*CP*GP*AP*GP*GP*GP*AP*GP*CP*IP*AP*GP*GP*G)-3') (1 entity in total) |
Functional Keywords | agcga-quadruplex, agcga-quadruplex family, g-g n1-carboniyl symmetric base pair, plekhg3 gene, dna, inosine |
Biological source | Homo sapiens |
Total number of polymer chains | 2 |
Total formula weight | 9500.14 |
Authors | Kocman, V.,Plavec, J. (deposition date: 2016-10-19, release date: 2017-05-31, Last modification date: 2024-05-15) |
Primary citation | Kocman, V.,Plavec, J. Tetrahelical structural family adopted by AGCGA-rich regulatory DNA regions. Nat Commun, 8:15355-15355, 2017 Cited by PubMed: 28513602DOI: 10.1038/ncomms15355 PDB entries with the same primary citation |
Experimental method | SOLUTION NMR |
Structure validation
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