5M1R

X-ray structure of human G166D PGK-1 mutant

Summary for 5M1R

• Entry DOI: 10.2210/pdb5m1r/pdb
• Descriptor: Phosphoglycerate kinase 1, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: phosphoglycerate kinase, single nucleotide polymorphism derived mutant g166d, transferase
• Biological source: Homo sapiens (Human)
• Total number of polymer chains: 1
• Total formula weight: 45075.27

Authors

Ilari, A.,Cipollone, A.,Fiorillo, A.,Petrosino, M. (deposition date: 2016-10-10, release date: 2017-12-20, Last modification date: 2024-01-17)

• Primary citation: Fiorillo, A.,Petrosino, M.,Ilari, A.,Pasquo, A.,Cipollone, A.,Maggi, M.,Chiaraluce, R.,Consalvi, V.; The phosphoglycerate kinase 1 variants found in carcinoma cells display different catalytic activity and conformational stability compared to the native enzyme.; PLoS ONE, 13:e0199191-e0199191, 2018; PubMed: 29995887; DOI: 10.1371/journal.pone.0199191

Experimental method

X-RAY DIFFRACTION (1.64 Å)