5LYG

CRYSTAL STRUCTURE OF INTRACELLULAR B30.2 DOMAIN OF BTN3A1 BOUND TO MALONATE

Summary for 5LYG

Entry DOI	10.2210/pdb5lyg/pdb
Descriptor	Butyrophilin subfamily 3 member A1, 1,2-ETHANEDIOL, MALONATE ION, ... (4 entities in total)
Functional Keywords	b30.2, butyrophilin, signaling protein
Biological source	Homo sapiens (Human)
Cellular location	Cell membrane ; Single- pass type I membrane protein : O00481
Total number of polymer chains	1
Total formula weight	21777.70
Authors	Mohammed, F.,Baker, A.T.,Salim, M.,Willcox, B.E. (deposition date: 2016-09-28, release date: 2017-09-13, Last modification date: 2024-05-08)
Primary citation	Salim, M.,Knowles, T.J.,Baker, A.T.,Davey, M.S.,Jeeves, M.,Sridhar, P.,Wilkie, J.,Willcox, C.R.,Kadri, H.,Taher, T.E.,Vantourout, P.,Hayday, A.,Mehellou, Y.,Mohammed, F.,Willcox, B.E. BTN3A1 Discriminates gamma delta T Cell Phosphoantigens from Nonantigenic Small Molecules via a Conformational Sensor in Its B30.2 Domain. ACS Chem. Biol., 12:2631-2643, 2017 Cited by PubMed: 28862425 DOI: 10.1021/acschembio.7b00694 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.6 Å)

Structure validation