5LXT
Tubulin-Discodermolide complex
Summary for 5LXT
Entry DOI | 10.2210/pdb5lxt/pdb |
Related | 4I4T 4I50 |
Descriptor | Tubulin alpha-1B chain, (+)-Discodermolide, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, ... (12 entities in total) |
Functional Keywords | cell cycle, tubulin fold, cytoskeleton, microtubule, discodermolide |
Biological source | Rattus norvegicus (Rat) More |
Cellular location | Cytoplasm, cytoskeleton: P81947 Q6B856 Golgi apparatus : P63043 |
Total number of polymer chains | 6 |
Total formula weight | 265733.95 |
Authors | Prota, A.E.,Steinmetz, M.O. (deposition date: 2016-09-22, release date: 2017-03-01, Last modification date: 2024-01-17) |
Primary citation | Prota, A.E.,Bargsten, K.,Redondo-Horcajo, M.,Smith, A.B.,Yang, C.H.,McDaid, H.M.,Paterson, I.,Horwitz, S.B.,Fernando Diaz, J.,Steinmetz, M.O. Structural Basis of Microtubule Stabilization by Discodermolide. Chembiochem, 18:905-909, 2017 Cited by PubMed: 28207984DOI: 10.1002/cbic.201600696 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.9 Å) |
Structure validation
Download full validation report