5LTH
Crystal structure of the alpha subunit of heme dependent oxidative N-demethylase (HODM) in complex with the dimethylamine substrate
Summary for 5LTH
Entry DOI | 10.2210/pdb5lth/pdb |
Descriptor | heme dependent oxidative N-demethylase, PROTOPORPHYRIN IX CONTAINING FE, DIMETHYLAMINE, ... (6 entities in total) |
Functional Keywords | heme binding, pas domain, amine oxidase, dimethylamine, oxidoreductase |
Biological source | Pseudomonas mendocina |
Total number of polymer chains | 1 |
Total formula weight | 40952.26 |
Authors | Ortmayer, M.,Leys, D. (deposition date: 2016-09-06, release date: 2016-11-09, Last modification date: 2024-01-17) |
Primary citation | Ortmayer, M.,Lafite, P.,Menon, B.R.,Tralau, T.,Fisher, K.,Denkhaus, L.,Scrutton, N.S.,Rigby, S.E.,Munro, A.W.,Hay, S.,Leys, D. An oxidative N-demethylase reveals PAS transition from ubiquitous sensor to enzyme. Nature, 539:593-597, 2016 Cited by PubMed: 27851736DOI: 10.1038/nature20159 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.76 Å) |
Structure validation
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